Start Low, Go Slow, See What You Can Learn…

My next-door neighbor works for Disney Studios. She has worked for them for 19 years. She posts pictures of herself on Facebook with Mickey Mouse and fairy princesses… I post information about treating chronic illness… Hmm.

I haven’t see a post from her in a while. I think she unfriended me for too many depressing posts.… My mother tells me that I was pretty serious right out of the starting gate… I guess so.

At this point, there are seven posts in the Treating Chronic Illness Series. You may have tried to lay in a foundation that provides support for the entire methylation pathway with All in One, Dr. Amy Yasko’s methyl group formation supporting multivitamin. You want to get methyl group formation happening as soon as possible.

You want to support the methyl group pool in your body with optimal supplementation for your genetics. If you have major genetic blocks to methyl group formation, you will need to supplement methyl groups, but there is such a thing as too many….

Right after All in One, you try to put in a bit of DHA, docosahexaenoic acid. DHA is the omega 3 fatty acid found in fish oil.  DHA enhances the activation of what Dr. Amy calls ‘the shortcut’ to methyl group formation, the biochemical pathway that goes between homocysteine and methionine in the pathway depicted below. This route produces methyl groups that your body can use, but it is not subject to the interferences that ‘the long route’ is subject to.

You can read more about this pathway in the free e book The Methyl Group: What It Can Do for You on the home page of my web Chapter 3 details the biochemistry that I am describing here. For copies of previous articles in the Treating Chronic Illness Series, click on the Blog button in the navigation bar of that web site. The Treating Chronic Illness Series started in January 2016.

After All in One and DHA, try a tiny amount of Phosphatidyl Serine Complex, (PS/PC/PE). It is also shortcut support. There are many Phosphatidyl Serine Complexes with different formulations out there, so use Dr. Amy’s formulation. It has a broad range of the necessary supplements in it. Nature’s Way has a similar formulation that you may be able to access from Emerson Ecologics.

Once again, start low and go slow. This caveat applies to everything you start. There is a tremendous amount of information in what happens when you start a supplement. You do not want to miss it. If you are taking multiple supplements and you feel awful, you don’t know if something about the supplement is making you feel bad, or if it is your illness. You need to back off of everything you are taking and see where you settle out. Then you start them again one at a time in small amounts to see how you react to them. You may be able to take a tiny amount of a substance you need, but more may give you symptoms. It’s OK to just stay with the tiny amount. You may be able to increase it later, or you may not. Just keep collecting information.

If you are giving yourself symptoms with something you are taking, then you are not going to know which direction is up as you proceed. Stop everything. See how you feel. Then start again one supplement at a time in tiny amounts to make discernments about what that substance does to you.

Given what you know about what that particular substance does in your body, and what symptoms it produced in you when you took it, you can make certain assumptions about the state of affairs in your system. This does not replace testing, but it is a huge hint about what is going on.

It is up to YOU to learn about treating your chronic illness successfully…

You need to know about the role of optimizing both methyl group production and your capacity for methylation in order to be healthy.

This is your opportunity. 

My Tuesday evening calls are ongoing.

They happen every week. There is no charge to come to the call.  It is a free forum where you can ask your questions.  It’s a great way to answer your most pressing questions, clear up confusion, overcome the obstacles you may be having, and get on the path to wellness.

The time:  Tuesday at 5:00 PM Pacific Time

(8:00 PM Eastern, 7:00 PM Central, 6:00 PM Mountain)

The number to call in the US: (605) 562-3140

The access code: 691392#
International access numbers are linked here.
Join us to inform yourself so that you can be proactive about your health!


So excellent!  I literally learn something on every single call and I get clarification on things that have been lingering on my mind…


You are giving people a huge gift by empowering them…It’s about helping the patient become their own healer by taking them to a higher level of consciousness…

Thank you so much Dr. Mullan.  Thank you so, so much for everything you do.

Wow!  I have to tell you, this was such an uplifting call.  It’s so nice to hear good news especially about a child.  Anxiety, OCD and a host of other mental/psychiatric symptoms have been a huge hurdle for me.  So to hear this story of all those awful symptoms totally going away is such a bright light for me!!!!

This is brilliant.  I hope a lot of people not doing methylation work will see this.  I wish I’d seen this before I started doing daily injections of B12 and folic acid and ended up in a crisis. Maybe had I known to have the genetic methylation stuff going, the IV therapies I did that really helped would not have been so traumatic…


Nancy Mullan MD

Author, lecturer, clinician,
Dr. Nancy Mullan is best known for her natural treatment of chronic illness, including Autism Spectrum Disorders, Lyme and MTHFR+.

2829 Burbank Blvd., Suite 202, Burbank CA  91505
Telephone/Fax: (818) 954-9267


About Nancy Mullan, MD

Some people call Dr. Nancy Mullan the MTHFR genetic medicine expert. Dr. Mullan works with people who are struggling with chronic disease or other significant illness, who are willing to use diet and genetics-based nutritional supplementation, and who want to increase wellbeing and energy, enhance immunity, lift mood, fine-tune genetic function, and get their lives back. Dr. Mullan has studied at a number of exceptional institutions: the University of Pennsylvania, Tufts University School of Medicine, and the University of Chicago Hospitals and Clinics. She excels at integrating the results of biochemical and genetic testing into sustained clinical improvement for you. She has succeeded with patients who confounded the specialists at Massachusetts General Hospital, the Mayo Clinic, the Cleveland Clinic, Stanford, and many well-known integrative medical doctors. When recommending her, her patients say, “This is the woman you need to talk to. She really knows how to handle tough clinical problems.” Dr. Mullan's specialty areas are MTHFR+, methylation genetics, and genetics-based nutritional supplementation. Within this context, she most often works with Chronic Fatigue Syndrome, Lyme Disease, Psychiatric Disorders, Autism Spectrum Disorders, Women’s Health Issues, Thyroid Disorder, Gastrointestinal Disorder, and Heavy Metal Toxicity.
This entry was posted in Treating Chronic Illness Series. Bookmark the permalink.