So, What’s Next?

After supporting the shortcut pathway to produce methyl groups, and putting in lithium to get B12 into the cell, next you turn to dealing with your gastrointestinal tract and mineral balance.

There are things you can do right away to deal with gastrointestinal balance.  You should recognize that it is very likely to be an issue, even if you think you do not have GI symptoms. If you are middle-aged or older, you probably need digestive enzymes. If you are younger than middle age and have GI symptoms, definitely take a digestive enzyme with your meals. Don’t wait for testing to get back. Even when you are eating plenty of protein, your amino acids may be low because of compromised digestion, and digestive enzymes should help that.

Protein is hard to digest. Protein is digested down into amino acids. Enzymes are made out of amino acids. People who are chronically ill often have impaired digestion and hence low amino acid levels. You can’t make the enzymes in the methylation process with low amino acids. Digestive enzymes help with this.

Your body’s production of digestive enzymes starts to decline in middle age. When that happens, undigested food goes through your GI tract, which slows the transit time of the material in your intestines. Anything you do not digest is left for problem organisms to use, which usually means trouble.

If you are chronically ill, you have an increased chance of having parasites. Parasitology testing from standard labs is high in false negatives. You need to use a specialty lab or a specific doctor who comes well-recommended for this. If you have a parasite, you can go around and around with your GI tract and never get it balanced.

Gastrointestinal transit time is also something that you can work on right away. You do not want material sitting in your GI tract. There should be only 12 – 18 hours between having eaten a food and having eliminated what is left of it. This means if you are eating three meals a day, you should be eliminating two or three times a day.  Constipation is deadly. One of the ways in which your body culls the organisms in your GI tract is by evacuating them. If evacuation is slowed down, the organisms have the chance to over grow.  What happens when you leave food in the refrigerator too long? It gets moldy. The same thing happens in your GI tract, and mold (yeast) there results in problems.

To read previous topics in the Treating Chronic Illness Series, click on the Blog button in the navigation bar of The Treating Chronic Illness Series started in January 2016.

It is up to YOU to learn about treating your chronic illness successfully…

You need to know about the role of optimizing both methyl group production and your capacity for methylation in order to be healthy.

This is your opportunity.




About Nancy Mullan, MD

Some people call Dr. Nancy Mullan the MTHFR genetic medicine expert. Dr. Mullan works with people who are struggling with chronic disease or other significant illness, who are willing to use diet and genetics-based nutritional supplementation, and who want to increase wellbeing and energy, enhance immunity, lift mood, fine-tune genetic function, and get their lives back. Dr. Mullan has studied at a number of exceptional institutions: the University of Pennsylvania, Tufts University School of Medicine, and the University of Chicago Hospitals and Clinics. She excels at integrating the results of biochemical and genetic testing into sustained clinical improvement for you. She has succeeded with patients who confounded the specialists at Massachusetts General Hospital, the Mayo Clinic, the Cleveland Clinic, Stanford, and many well-known integrative medical doctors. When recommending her, her patients say, “This is the woman you need to talk to. She really knows how to handle tough clinical problems.” Dr. Mullan's specialty areas are MTHFR+, methylation genetics, and genetics-based nutritional supplementation. Within this context, she most often works with Chronic Fatigue Syndrome, Lyme Disease, Psychiatric Disorders, Autism Spectrum Disorders, Women’s Health Issues, Thyroid Disorder, Gastrointestinal Disorder, and Heavy Metal Toxicity.
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